Guillain-Barré Syndrome (GBS)

Context

Recently, the Union Health Ministry organised a team to assess the situation in Maharashtra after the sudden outbreak of the Guillain-Barré Syndrome (GBS).

Relevance:

GS-02 (Health)

Key Highlights of the Article

  • 73 cases of GBS were reported, with 14 patients on ventilators. Rapid Response Teams have been deployed by the government.
  • GBS is a rare autoimmune disorder that damages peripheral nerves, often triggered by bacterial or viral infections.

Dimensions of the Article

  • What is Guillain-Barré syndrome?
  • How Does GBS Affect the Body?
  • How is GBS treated?

What is Guillain-Barré syndrome?

  • It is a rare autoimmune disorder where the body’s immune system attacks its own peripheral nerves.
  • It may be caused by an acute bacterial or viral infection such as those caused by Campylobacter jejuni, the flu virus, or Zika virus and in some cases even due to a particular type of vaccine.
  • This results in muscle weakness and, in severe cases, leads to paralysis.
  • While the exact causes remain unclear, GBS often follows bacterial or viral infections.

How Does GBS Affect the Body?

  • The condition impacts the peripheral nervous system, damaging the myelin sheath around nerves.
  • This disrupts nerve signals, leading to symptoms like tingling, muscle weakness, and even paralysis in severe cases.
  • It can also affect chest muscles, making it difficult to breathe, and may interfere with swallowing and speaking.

How is GBS treated?

  • While there is no definitive cure, treatments like plasma exchange and intravenous immunoglobulin therapy can help manage the condition.
  • Rehabilitation and supportive care, including physical therapy, play a significant role in recovery. In severe cases, intensive care may be required to manage complications.

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