Chitra Magna, an innovative RNA extraction kit, has been developed by Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST)
- The protocol for the kit uses magnetic nanoparticles to capture and concentrate the RNA from the patient sample.
- The magnetic nanoparticle beads bind to the viral RNA and, when exposed to a magnetic field, give a highly purified and concentrated level of RNA.
- As the yield of PCR or LAMP test is dependent on getting an adequate quantity of viral RNA, this innovation enhances the chances of identifying positive cases.
- Chitra Magna can be used to extract high purity RNA from patient samples not only for LAMP testing but also for the RT-PCR test.
Significance : This is of significant advantage because even if some viral RNA disintegrates during storage and transportation of the patient samples, all of it is captured by the magnetic bead-based extraction technology.