Polyoxometalates (POMs) 

#GS3 #Science&Technology 

Scientists from the Institute of Nano Science & Technology (INST), Mohali, an autonomous institute of the Department of Science and Technology Government of India, have synthesized a novel inorganic-organic hybrid compound that can inhibit breast, lung, and liver cancer cells, opening up new possibilities for metallodrugs. 

  • The solid compound based on phosphomolybdate cluster, an inorganic salt of phosphomolybdic acid, belongs to the Polyoxometalates (POMs) family, which had earlier been identified to have antitumor potential. 
  • POMs are an evolving class of inorganic metal oxides, which over the last decades, established promising biological activities by the virtue of their great diversity in structures and properties. 
  • The in vitro results showed that this hybrid solid is less toxic towards normal cells, and its antitumor activity was also found to be comparable with that of a routinely used chemotherapeutic agent, Methotrexate (MTX). 
  • The in vitro results showed that this hybrid solid is less toxic towards normal cells, and its antitumor activity was also found to be comparable with that of a routinely used chemotherapeutic agent, Methotrexate (MTX). 
Print Friendly and PDF
blog comments powered by Disqus