Post-Covid review in children finds severe heart damage 

#GS3 #Health 

Multisystem inflammatory syndrome in children (MIS-C), believed to be linked to Covid-19, damages the heart says a medical literature review published in EClinicalMedicine, a journal of The Lancet. 

  • The heart damage is so severe that some children will need lifelong monitoring and interventions, according to senior author Dr Alvaro Moreira of The University of Texas Health Science Center at San Antonio. 
  • “According to the literature, children did not need to exhibit the classic upper respiratory symptoms of Covid-19 to develop MIS-C, which is frightening. Children might have no symptoms, no one knew they had the disease, and a few weeks later, they may develop this exaggerated inflammation in the body,” Moreira said in a statement. 
  • The team reviewed 662 MIS-C cases reported worldwide between January 1 and July 25. Eleven of the children died. Ninety per cent had an ECG test and 54% of the results were abnormal. The heart damage included: 
  • Dilation of coronary blood vessels, a phenomenon also seen in Kawasaki disease. 
  • Depressed ejection fraction, indicating a reduced ability for the heart to pump oxygenated blood to tissues. 

What is MIS-C? 

  • Multisystem inflammatory syndrome in children (MIS-C) is a condition where different body parts can become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs.  
  • Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhoea, neck pain, rash, bloodshot eyes, or feeling extra tired. We do not yet know what causes MIS-C.  
  • However, many children with MIS-C had the virus that causes COVID-19, or had been around someone with COVID-19. 

Business Reform Action Plan (BRAP) ranking of states 

Union Finance Minister announced the Business Reform Action Plan (BRAP) ranking of states. 

  • Ranking of States based on the implementation of the Business Reform Action Plan started in the year 2015. 
  • The current ranking announced is for 2018 – 19 (previously, the ranking was done was 2015, 2016 and 2017-18). 

Need for the Business Reform Action Plan 

  • The larger objective of attracting investments and increasing the Ease of Doing Business in each State was sought to be achieved by introducing an element of healthy competition through a system of ranking states based on their performance in the implementation of the Business Reform Action Plan. 
  • The ranking this time gives full weightage to the feedback from over thirty thousand respondents at the ground level, who gave their opinion about the effectiveness of the reforms. 
  • State rankings will help attract investments, foster healthy competition and increase the Ease of Doing Business in each State. 

Business Reform Action Plan 2018-19:

  • This ranking includes 180 reform points covering 12 business regulatory areas such as Access to Information, Single Window System, Labour, Environment, etc. 
  • The top ten states under the BRAP 2019 are: 
    • Andhra Pradesh 
    • Uttar Pradesh 
    • Telangana 
    • Madhya Pradesh 
    • Jharkhand 
    • Chhattisgarh 
    • Himachal Pradesh 
    • Rajasthan 
    • West Bengal 
    • Gujarat 
  • The state which showed the most improvement since the 2018 ranking is Uttar Pradesh which moved from rank 12 in 2018 to rank 2 in 2019. 
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