Allergic reactions to Covid-19 vaccines


In the US, where the Food and Drug Administration (FDA) has granted emergency use approvals to the Covid-19 vaccines from Pfizer-BioNTech and Moderna, concerns have been raised, that some people have possible allergic reactions to Covid-19 vaccines. 

  • A team of experts has now examined the relevant information and offered reassurance that the vaccines can be given safely, even to people with food or medication allergies. 
  • The review notes that allergic reactions to vaccines in general are rare, with a rate of about 1.3 per 1 million people.
  • The authors summarise what is currently known about allergic reactions to vaccines like the ones developed against Covid-19, and propose detailed advice so that individuals with different allergy histories can safely receive their first Covid-19 vaccine. 
  • They also outline steps on safely receiving the second dose in individuals who develop a reaction to their first dose.
  • The guidelines are built upon the recommendations of US regulatory agencies and provide clear steps to the medical community on how to safely administer both doses of the vaccine in individuals with allergic histories.
  • The experts stress that Covid-19 vaccine clinics will be monitoring all patients for 15 to 30 minutes and can manage any allergic reactions that occur. 
  • The individuals with a history of anaphylaxis to an injectable drug or vaccine containing the compounds polyethylene glycol or polysorbate speak with their allergists before being vaccinated. 
  • The patients with severe allergies to foods, oral drugs, latex, or venom can safely receive the Covid-19 vaccines.
  • In the US, after a review of the data related to allergic reactions, the FDA recommended that the vaccines be withheld only from individuals with a history of severe allergic reactions to any component of the Covid-19 vaccine. 
  • The Centers for Disease Control and Prevention (CDC) advised that all patients be observed for 15 minutes post-vaccination by staff who can identify and manage such reactions. 
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